外部利用により発表された論文
2023
Hirao, K.; Speciale, I.; Notaro, A.; Manabe, Y.; Teramoto, Y.; Sato, T.; Atomi, H.; Molinaro, A.; Ueda, Y.; De Castro, C.; Fukase, K. Structural Determination and Chemical Synthesis of the N ‐Glycan from the Hyperthermophilic Archaeon Thermococcus Kodakarensis. Angew. Chemie Int. Ed. 2023, 62 (13). https://doi.org/10.1002/anie.202218655.
Mizuno, F.; Aoki, S.; Matsugami, A.; Hayashi, F.; Nishimura, C. The Residual Structure of Unfolded Proteins Was Elucidated from the Standard Deviation of NMR Intensity Differences. Protein Pept. Lett. 2023, 30 (2), 103–107. https://doi.org/10.2174/0929866530666230104140830.
2022
Gu, H.; Kato, T.; Kumeta, H.; Kumaki, Y.; Tsukamoto, T.; Kikukawa, T.; Demura, M.; Ishida, H.; Vogel, H. J.; Aizawa, T. Three-Dimensional Structure of the Antimicrobial Peptide Cecropin P1 in Dodecylphosphocholine Micelles and the Role of the C-Terminal Residues. ACS Omega 2022, 7 (36), 31924–31934. https://doi.org/10.1021/acsomega.2c02778.
Iizuka, T.; Aizawa, T. Japanese Cedar Pollinosis and Fruit Allergy Caused by GRPs. Nihon Shoni Arerugi Gakkaishi. Japanese J. Pediatr. Allergy Clin. Immunol. 2022, 36 (2), 157–162. https://doi.org/10.3388/jspaci.36.157.
Komatsu, Y.; Kumakura, D.; Seto, N.; Izumi, H.; Takeda, Y.; Ohnishi, Y.; Nakaoka, S.; Aizawa, T. Dynamic Associations of Milk Components With the Infant Gut Microbiome and Fecal Metabolites in a Mother–Infant Model by Microbiome, NMR Metabolomic, and Time-Series Clustering Analyses. Front. Nutr. 2022, 8. https://doi.org/10.3389/fnut.2021.813690.
Kubo, K.; Watanabe, H.; Kumeta, H.; Aizawa, T.; Seki, C.; Nakano, H.; Tokuraku, K.; Uwai, K. Chemical Analysis of Amyloid β Aggregation Inhibitors Derived from Geranium Thunbergii. Bioorg. Med. Chem. 2022, 68, 116840. https://doi.org/10.1016/j.bmc.2022.116840.
Kuroda, K.; Narihiro, T.; Nakaya, Y.; Noguchi, T. Q. P.; Maeda, R.; Nobu, M. K.; Ohnishi, Y.; Kumaki, Y.; Aizawa, T.; Satoh, H. Elucidation of the Biodegradation Pathways of Bis(2-Hydroxyethyl) Terephthalate and Dimethyl Terephthalate under Anaerobic Conditions Revealed by Enrichment Culture and Microbiome Analysis. Chem. Eng. J. 2022, 450, 137916. https://doi.org/10.1016/j.cej.2022.137916.
Nagano, K.; Kamimura, T.; Kawai, G. Interaction between a Fluoroquinolone Derivative and RNAs with a Single Bulge. J. Biochem. 2022, 171 (2), 239–244. https://doi.org/10.1093/jb/mvab124.
Okuda, Y.; Miyoshi, R.; Kamo, T.; Fujisawa, T.; Nagae, T.; Mishima, M.; Eki, T.; Hirose, Y.; Unno, M. Raman Spectroscopy of an Atypical C15- E , Syn Bilin Chromophore in Cyanobacteriochrome RcaE. J. Phys. Chem. B 2022, 126 (4), 813–821. https://doi.org/10.1021/acs.jpcb.1c09652.
Sayeesh, P. M.; Ikeya, T.; Sugasawa, H.; Watanabe, R.; Mishima, M.; Inomata, K.; Ito, Y. Insight into the C-Terminal SH3 Domain Mediated Binding of Drosophila Drk to Sos and Dos. Biochem. Biophys. Res. Commun. 2022, 625, 87–93. https://doi.org/10.1016/j.bbrc.2022.08.007.
Suzuki, Y.; Higashi, T.; Yamamoto, T.; Okamura, H.; Sato, T. K.; Asakura, T. Presence of β-Turn Structure in Recombinant Spider Silk Dissolved in Formic Acid Revealed with NMR. Molecules 2022, 27 (2), 511. https://doi.org/10.3390/molecules27020511.
Takase, N.; Otsu, M.; Hirakata, S.; Ishizu, H.; Siomi, M. C.; Kawai, G. T-Hairpin Structure Found in the RNA Element Involved in PiRNA Biogenesis. RNA 2022, 28 (4), 541–550. https://doi.org/10.1261/rna.078967.121.
Tao, H.; Mori, T.; Chen, H.; Lyu, S.; Nonoyama, A.; Lee, S.; Abe, I. Molecular Insights into the Unusually Promiscuous and Catalytically Versatile Fe(II)/α-Ketoglutarate-Dependent Oxygenase SptF. Nat. Commun. 2022, 13 (1), 95. https://doi.org/10.1038/s41467-021-27636-3.
Villones, L. L.; Ludwig, A.-K.; Kumeta, H.; Kikuchi, S.; Ochi, R.; Aizawa, T.; Nishimura, S.-I.; Gabius, H.-J.; Hinou, H. Exploring the In Situ Pairing of Human Galectins toward Synthetic O-Mannosylated Core M1 Glycopeptides of α-Dystroglycan. Sci. Rep. 2022, 12 (1), 17800. https://doi.org/10.1038/s41598-022-22758-0.
2021
Tsukakoshi, K.; Yamagishi, Y.; Kanazashi, M.; Nakama, K.; Oshikawa, D.; Savory, N.; Matsugami, A.; Hayashi, F.; Lee, J.; Saito, T.; Sode, K.; Khunathai, K.; Kuno, H.; Ikebukuro, K. G-Quadruplex-Forming Aptamer Enhances the Peroxidase Activity of Myoglobin against Luminol. Nucleic Acids Res. 2021, 49 (11), 6069–6081. https://doi.org/10.1093/nar/gkab388.
Kamiya, K.; Itoh, H.; Inoue, M. Generation and Biological Evaluation of Degraded Derivatives of the Three E / Z -Isomers of Yaku’amide B. J. Nat. Prod. 2021, 84 (6), 1854–1859. https://doi.org/10.1021/acs.jnatprod.1c00339.
Obayashi, C. M.; Shinohara, Y.; Masuda, T.; Kawai, G. Influence of the 5′-Terminal Sequences on the 5′-UTR Structure of HIV-1 Genomic RNA. Sci. Rep. 2021, 11 (1). https://doi.org/10.1038/s41598-021-90427-9.
Nishiyama, R.; Ojima, T.; Ohnishi, Y.; Kumaki, Y.; Aizawa, T.; Inoue, A. An Oxidative Metabolic Pathway of 4-Deoxy-L-Erythro-5-Hexoseulose Uronic Acid (DEHU) from Alginate in an Alginate-Assimilating Bacterium. Commun. Biol. 2021, 4 (1), 1254. https://doi.org/10.1038/s42003-021-02786-8.
Saio, T.; Hiramatsu, S.; Asada, M.; Nakagawa, H.; Shimizu, K.; Kumeta, H.; Nakamura, T.; Ishimori, K. Conformational Ensemble of a Multidomain Protein Explored by Gd3+ Electron Paramagnetic Resonance. Biophys. J. 2021, 120 (15), 2943–2951. https://doi.org/10.1016/j.bpj.2021.06.033.
Okumura, M.; Kanemura, S.; Matsusaki, M.; Kinoshita, M.; Saio, T.; Ito, D.; Hirayama, C.; Kumeta, H.; Watabe, M.; Amagai, Y.; Lee, Y.-H.; Akiyama, S.; Inaba, K. A Unique Leucine-Valine Adhesive Motif Supports Structure and Function of Protein Disulfide Isomerase P5 via Dimerization. Structure 2021, 29 (12), 1357-1370.e6. https://doi.org/10.1016/j.str.2021.03.016.
Sato, Y.; Matsugami, A.; Watanabe, S.; Hayashi, F.; Arai, M.; Kigawa, T.; Nishimura, C. Changes in Dynamic and Static Structures of the <scp>HIV</Scp> ‐1 P24 Capsid Protein N‐domain Caused by Amino‐acid Substitution Are Associated with Its Viral Viability. Protein Sci. 2021, 30 (11), 2233–2245. https://doi.org/10.1002/pro.4184.
Nagae, T.; Unno, M.; Koizumi, T.; Miyanoiri, Y.; Fujisawa, T.; Masui, K.; Kamo, T.; Wada, K.; Eki, T.; Ito, Y.; Hirose, Y.; Mishima, M. Structural Basis of the Protochromic Green/Red Photocycle of the Chromatic Acclimation Sensor RcaE. Proc. Natl. Acad. Sci. 2021, 118 (20). https://doi.org/10.1073/pnas.2024583118.
Barra, L.; Awakawa, T.; Shirai, K.; Hu, Z.; Bashiri, G.; Abe, I. β-NAD as a Building Block in Natural Product Biosynthesis. Nature 2021, 600 (7890), 754–758. https://doi.org/10.1038/s41586-021-04214-7.
Li, X.; Awakawa, T.; Mori, T.; Ling, M.; Hu, D.; Wu, B.; Abe, I. Heterodimeric Non-Heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J. Am. Chem. Soc. 2021, 143 (50), 21425–21432. https://doi.org/10.1021/jacs.1c11548.
Unno, M.; Hirose, Y.; Mishima, M.; Kikukawa, T.; Fujisawa, T.; Iwata, T.; Tamogami, J. Spectroscopic Approach for Exploring Structure and Function of Photoreceptor Proteins. Biophys. Physicobiology 2021, 18, 127–130. https://doi.org/10.2142/biophysico.bppb-v18.014.
Kamiya, K.; Miura, K.; Itoh, H.; Inoue, M. Divergent Solid‐Phase Synthesis and Biological Evaluation of Yaku’amide B and Its Seven E / Z Isomers. Chem. – A Eur. J. 2021, 27 (3), 1088–1093. https://doi.org/10.1002/chem.202003858.
Komatsu, Y.; Wada, Y.; Izumi, H.; Shimizu, T.; Takeda, Y.; Aizawa, T. 1 H NMR Metabolomic and Transcriptomic Analyses Reveal Urinary Metabolites as Biomarker Candidates in Response to Protein Undernutrition in Adult Rats. Br. J. Nutr. 2021, 125 (6), 633–643. https://doi.org/10.1017/S0007114520003281.
Satake, M.; Irie, R.; Holland, P. T.; Harwood, D. T.; Shi, F.; Itoh, Y.; Hayashi, F.; Zhang, H. Brevisulcenals-A1 and A2, Sulfate Esters of Brevisulcenals, Isolated from the Red Tide Dinoflagellate Karenia Brevisulcata. Toxins (Basel). 2021, 13 (2), 82. https://doi.org/10.3390/toxins13020082.
2020
Yagi, H.; Yanaka, S.; Yogo, R.; Ikeda, A.; Onitsuka, M.; Yamazaki, T.; Kato, T.; Park, E. Y.; Yokoyama, J.; Kato, K. Silkworm Pupae Function as Efficient Producers of Recombinant Glycoproteins with Stable-Isotope Labeling. Biomolecules 2020, 10 (11), 1–12. https://doi.org/10.3390/biom10111482.
Hatanaka, T.; Kikkawa, N.; Matsugami, A.; Hosokawa, Y.; Hayashi, F.; Ishida, N. The Origins of Binding Specificity of a Lanthanide Ion Binding Peptide. Sci. Rep. 2020, 10 (1), 19468. https://doi.org/10.1038/s41598-020-76527-y.
2019
Yamasaki, K.; Kubota, T.; Yamasaki, T.; Nagashima, I.; Shimizu, H.; Terada, R.; Nishigami, H.; Kang, J.; Tateno, M.; Tateno, H. Structural Basis for Specific Recognition of Core Fucosylation in N-Glycans by Pholiota Squarrosa Lectin (PhoSL). Glycobiology 2019, 29 (7), 576–587. https://doi.org/10.1093/glycob/cwz025.
Itoh, H.; Tokumoto, K.; Kaji, T.; Paudel, A.; Panthee, S.; Hamamoto, H.; Sekimizu, K.; Inoue, M. Development of a High-Throughput Strategy for Discovery of Potent Analogues of Antibiotic Lysocin E. Nat. Commun. 2019, 10 (1), 2992. https://doi.org/10.1038/s41467-019-10754-4.
2018
Yamasaki, K.; Yamasaki, T.; Tateno, H. The Trimeric Solution Structure and Fucose-Binding Mechanism of the Core Fucosylation-Specific Lectin PhoSL. Sci. Rep. 2018, 8 (1), 7740. https://doi.org/10.1038/s41598-018-25630-2.
Urabe, D.; Nakagawa, Y.; Mukai, K.; Fukushima, K.; Aoki, N.; Itoh, H.; Nagatomo, M.; Inoue, M. Total Synthesis and Biological Evaluation of 19-Hydroxysarmentogenin-3 -O -α- l -Rhamnoside, Trewianin, and Their Aglycons. J. Org. Chem. 2018, 83 (22), 13888–13910. https://doi.org/10.1021/acs.joc.8b02219.
Hayata, A.; Itoh, H.; Inoue, M. Solid-Phase Total Synthesis and Dual Mechanism of Action of the Channel-Forming 48-Mer Peptide Polytheonamide B. J. Am. Chem. Soc. 2018, 140 (33), 10602–10611. https://doi.org/10.1021/jacs.8b06755.
2017
Yanaka, S.; Yamazaki, T.; Yogo, R.; Noda, M.; Uchiyama, S.; Yagi, H.; Kato, K. NMR Detection of Semi-Specific Antibody Interactions in Serum Environments. Molecules 2017, 22 (10). https://doi.org/10.3390/molecules22101619.
Otsu, M.; Kajikawa, M.; Okada, N.; Kawai, G. Solution Structure of a Reverse Transcriptase Recognition Site of a LINE RNA from Zebrafish. J. Biochem. 2017, 162 (4), 279–285. https://doi.org/10.1093/jb/mvx026.